Cancerul unui copil de 3 ani a dispărut după un tratament experimental: cum au reușit cercetătorii să reprogrameze celulele imunitare

An experimental therapy using genetically modified immune cells led to the complete disappearance of cancer in a three-year-old boy with metastatic hepatoblastoma. Despite previous treatments, the cancer returned, prompting inclusion in a clinical trial testing CAR-T therapy. Researchers modified T cells to target a specific protein found in liver cancer, resulting in significant tumor reduction after two doses. Follow-up showed no signs of cancer after 12 months, but further studies are needed to confirm the therapy's effectiveness for other patients. This case highlights the potential of CAR-T therapy for solid tumors, which has been challenging to apply compared to blood cancers.