Sepsis. Why do organs stop functioning?

Miguel Che Soares revisits his research on sepsis six years after his initial interview, highlighting advancements in understanding metabolic responses during infections. His team discovered that after an initial reliance on glucose, the body shifts to using fat as an energy source for survival. Soares is launching a new project, Sepsis-Atlas, to map genetic activity in adipose tissue of septic patients. Additionally, he received an ERC Advanced Grant for the KILLBILL project, investigating bilirubin's protective role against malaria. Despite funding challenges, Soares emphasizes the ongoing need for research to understand sepsis and improve patient outcomes.