"I returned to square one." Christina Applegate lived with a wrong diagnosis for five years.

Christina Applegate returned to her podcast "MeSsy" after a break, revealing she does not have multiple sclerosis. Despite the relief, she expressed that her health has worsened and she feels lost without a diagnosis. Dr. Marwa Kaisey discussed the prevalence of misdiagnosis in MS, noting that nearly 20% of those diagnosed may not actually have the disease. Applegate shared her struggles with mental health and the impact of the incorrect diagnosis on her life, stating she still faces significant health challenges.